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References 1.Obeid R, Heil SG, Verhoeven MMA, van den Heuvel EGHM, de Groot LCPGM, Eussen SJPM

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Although traditionally considered an inflammatory disorder of white matter, more recently it has become apparent that gray matter damage is also prominent and widespread, though the immune responses are less pronounced in this region, and therefore the radiological and pathological signatures more subtle